解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Germ cells' proliferation during testicular organogenesis in Wistar rat embryos and neonates [14.5, 18.5, 20.5 days post conception (dpc), birth (day 0), 1, 3, 5, 7 days post partum (dpp)] was evaluated via immunohistochemistry, using the PCNA and Ki-67 nuclear antibodies. Estimation of the reactive/total cell ratio, ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.09.004
更新日期:2008-02-01 00:00:00
abstract::The hydrogenosome, an organelle that produces molecular hydrogen and ATP from the oxidation of pyruvate or malate under anaerobic conditions, presents some characteristics common to mitochondria. The hydrogenosome of Tritrichomonas foetus, a cattle parasite, is a spherical organelle that presents a peripheral vesicle ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.09.006
更新日期:2008-02-01 00:00:00
abstract::2-Cys peroxiredoxins (PRDX) are novel antioxidant enzymes that eliminate the hydrogen peroxide in cells to protect the cellular components from reactive oxygen species. To evaluate whether 2-Cys PRDX family plays a role in human ciliary body, the expression of PRDX I, II and III on normal human ciliary body was invest...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.06.003
更新日期:2007-10-01 00:00:00
abstract::The role of phagocytosis in eliminating apoptotic spermatogenic cells caused by mono(2-ethylhexyl) phthalate (MEHP) was studied. Twenty-one-day-old C57Bl/6N male mice were given a single dose of 800 mg/kg MEHP in corn oil by oral gavage and sacrificed at 1, 3, 5, 7 and 9 days after initial exposure. At the same time, ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.04.002
更新日期:2007-08-01 00:00:00
abstract::Oligoryzomys flavescens, a common rodent of the temperate regions of South America, has been identified as a Hantavirus reservoir. There is still little information concerning its reproductive biology, which is essential to devise effective control measurement of natural populations. This rodent is a seasonal breeder ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.05.001
更新日期:2007-08-01 00:00:00
abstract::We established a human pancreatic carcinoma cell line, designated SPH, from cancerous ascites of a 57-year-old male patient with ductal adenocarcinoma of the pancreas. The cells have been cultured for 32 months with RPMI-1640 medium supplemental with 10% fetal calf serum. The population doubling time of this cell line...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.04.001
更新日期:2007-08-01 00:00:00
abstract::We examined the participation of MAPK and PKA in the Golgi complex disassembly caused by light-activated Calphostin C in HT-29 cells. When these cells were incubated with Calphostin C, fragmentation and dispersal of the Golgi complex was observed as assessed by immunofluorescence microscopy. Electron microscopy analys...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2007.03.001
更新日期:2007-06-01 00:00:00
abstract::The oxidative agent paraquat induced tail abnormalities during Xenopus laevis development. Specimens exposed from blastula to the tadpole stage revealed pear-shaped myocytes and irregular intersomitic boundaries. The histological feature of the axial musculature was evaluated in embryos sampled at significant stages o...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2006.03.002
更新日期:2006-06-01 00:00:00
abstract::Pituitary glands were removed from sexually mature female turtles (Chrysemys picta) and they were injected intraperitoneally (i.p.) into other mature females of the same species (experimental). In addition mature females of the same species received saline injection only (controls). Initially all the turtles used in t...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2006.02.001
更新日期:2006-06-01 00:00:00
abstract::The expression of alpha(1a)-adrenoreceptors (alpha(1a)-ARs) within the muscle spindles of rabbit masseter muscle was investigated. The alpha(1a)-ARs were detected by immunohistochemical fluorescent method and examined along the entire length of 109 cross serially sectioned spindles. The sympathetic fibers were visuali...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2005.12.003
更新日期:2006-04-01 00:00:00
abstract::The Australian lungfish, Neoceratodus forsteri, has a dentition consisting of enamel, mantle dentine and bone, enclosing circumdenteonal, core and interdenteonal dentines. Branching processes from cells that produce interdenteonal dentine leave the cell surface at different angles, with collagen fibrils aligned parall...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2006.01.001
更新日期:2006-04-01 00:00:00
abstract::Due to the recent importance assumed by the apoptotic process as a tool in the therapeutic protocols, we investigated the onset and rate of drug-induced apoptosis in a cell model of prostatic tumor: the DU-145 cells. The human prostatic cancer cells, DU-145, have been treated with pro-apoptotic substances like puromyc...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2005.06.006
更新日期:2005-10-01 00:00:00
abstract::The origin of midgut epithelium may begin either from yolk cells (energids), tips of stomo- and proctodaeum (ectoderm), inner layer (endoderm) or from both kinds of the above mentioned cells. The origin of the midgut epithelium in wingless insects (Apterygota) has still not been determined. In Thermobia domestica the ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2004.12.001
更新日期:2005-04-01 00:00:00
abstract::The present study reports on the ultrastructure features of spermatozoa and spermatogenesis of several species of Dysderidae (Dysdera crocata, Dysdera erythrina, Dysdera ninnii, Harpactea arguta, Harpactea piligera, Dasumia taeniifera). Dysderid spiders are known to possess a peculiar sperm transfer form known as syns...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2004.08.001
更新日期:2004-12-01 00:00:00
abstract::Reptilian epidermis contains two types of keratin, soft (alpha) and hard (beta). The biosynthesis and molecular weight of beta-keratin during differentiation of lizard epidermis have been studied by autoradiography, immunocytochemistry and immunoblotting. Tritiated proline is mainly incorporated into differentiating a...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2004.06.001
更新日期:2004-10-01 00:00:00
abstract::The second half of the 20th century has witnessed the birth and growth of biological ultrastructure research--a branch of cell biology in which electron microscopy plays an important role. After a humble start in around 1950, when only a limited arsenal of instrumentation was available, a wealth of auxiliary methodolo...
journal_title:Tissue & cell
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.tice.2003.11.001
更新日期:2004-04-01 00:00:00
abstract::The diabetes (db/db) and obese (ob/ob) genotype mutations induce a progressive, hypercytolipidemic condition within the endometrium of the female reproductive tract that promotes sterility and premature organ involution in C57BL/KsJ mice. The current studies focus on the ultrastructural changes that occur within the e...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/j.tice.2003.08.002
更新日期:2004-02-01 00:00:00
abstract::We have recently shown that down-regulation of mouse Thy28 (mThy28) protein expression appears to be accompanied by apoptotic processes. Thymocytes from mice contain moderate amounts of mThy28 protein and undergo proliferation, differentiation, or apoptosis during murine thymic maturation. As a first step to examine t...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00073-9
更新日期:2003-12-01 00:00:00
abstract::Spermatozoa and spermiogenesis of the prithine filistatid spider Wandella orana are described. The spider produces coenospermia, i.e. sperm aggregations that include several single sperm cells commonly surrounded by a secretion sheath. One sectioned coenospermium in W. orana contains at least five spermatozoa. During ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00054-5
更新日期:2003-10-01 00:00:00
abstract::We examined the development of serous (poison) cutaneous glands in larval and juvenile Scinax nasica (Hylidae) at the ultrastructural level. We describe the biosynthesis and maturation of the cutaneous poison in comparison with the corresponding processes in representatives of Discoglossidae, Leptodactylidae, Pelobati...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00049-1
更新日期:2003-08-01 00:00:00
abstract::The hydrozoa life cycle is characterized, in normal conditions, by the alternation of a post-larval benthic polyp and an adult pelagic medusa; however, some species of Hydrozoa react to environmental stress by reverting their life cycle: i.e. an adult medusa goes back to the juvenile stage of polyp. This very uncommon...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(03)00028-4
更新日期:2003-06-01 00:00:00
abstract::There is now strong evidence that the stem cells of many tissues reside in specialized structures termed niches. The stem cell niche functions to house and regulate symmetric and asymmetric mitosis of stem cells in mammalian skin, mouse and human bone marrow, mouse brain, gut, and hair follicle, and Drosophila ovary a...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00107-6
更新日期:2003-04-01 00:00:00
abstract::Lipid bodies (LB), lipid-rich inclusions abundantly present in cells engaged in inflammation, are specialized intracellular domains involved in generating inflammatory mediators, the eicosanoids. Since the acute Trypanosoma cruzi infection triggers a potent inflammatory reaction characterized by a great increase of pe...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00105-2
更新日期:2003-02-01 00:00:00
abstract::Using immunoelectronmicroscopy we analyzed qualitative and quantitatively the intracellular distribution of bothropasin, hemorrhagic factor 2 (HF2) and hemorrhagic factor 3 (HF3) in the venom secretory cells from adult snakes in the active (7 days after venom extraction) and in the resting (without venom extraction fo...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s004081660200068x
更新日期:2002-12-01 00:00:00
abstract::A morphological and ultrastructural study was carried out on the spermatophore and spermatodoses of some species of Orthoptera Tettigoniidae. From the results concerning the spermatophore it emerged that this structure has a morphological and ultrastructural organization represented by a dilated ampulla and a peduncle...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040816602000344
更新日期:2002-10-01 00:00:00
abstract::Spermiogenesis of the domestic sparrow was investigated with the light and electron microscopes and a step by step classification is proposed. Three cell populations corresponding to early, mid and late spermatids were easily divided according to their positions in the seminiferous epithelium. In addition to this init...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00017-4
更新日期:2002-08-01 00:00:00
abstract::The expression and localization of gap junctional proteins connexin (Cx) 26, 32, and 43 was examined in human dental pulp. Dental pulp tissues were obtained from human third molars immediately after extraction. Some pulp tissues were used for cell culture, and the rest for histological observations. Immunostaining for...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00028-9
更新日期:2002-06-01 00:00:00
abstract::Species that live in extreme conditions have specially adapted physiology and tissue/organ organisation. The adaptation of lymphoid organs to low temperatures in polar species could be an original field of study, indicating how the immune system works under extreme conditions. In fishes, the head kidney is a key organ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(02)00005-8
更新日期:2002-04-01 00:00:00
abstract::The receptor activator of NF-kappa B ligand (RANKL) and its decoy receptor, osteoprotegerin (OPG), are the important proteins involved in osteoclastogenesis. In this study, we investigated the expressions of RANKL and OPG in cultured human periodontal ligament cells derived from deciduous teeth (DPDL cells) and their ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2002.0223
更新日期:2002-02-01 00:00:00
abstract::The presence of stage-dependent occlusive junctions between adjacent Sertoli cells in the seminiferous epithelium of the crayfish testis was demonstrated by a lanthanum tracer study. The germinal epithelium did not appear to be compartmentalized, as evidenced by access of lanthanum to spermatogonia, spermatocytes, and...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2001.0211
更新日期:2001-12-01 00:00:00
abstract::Specific biomechanical characters and some structures possibly related to them were investigated in the skin of the toad Bufo marinus using tensile testing techniques (at constant strain till rupture) as well as morphological methods (histological, immunohistochemical and electronmicroscopical). Mechanical parameters ...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2001.0208
更新日期:2001-10-01 00:00:00
abstract::Keratinization in the epidermis of amphibians and the lungfish has been studied by electron microscopy, autoradiography and immunocytochemistry to determine whether histidine-rich proteins, filaggrin and loricrin are present. In the lungfish and amphibian tadpoles, anti-keratin antibodies (AE1 and AE3) stain the whole...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2001.0198
更新日期:2001-10-01 00:00:00
abstract::Aromatization of androgens into estrogens in rat testis is catalyzed by the microsomal enzyme cytochrome P450 aromatase. In this work, aromatase cellular site was investigated in prepuberal, peripuberal and postpuberal testis, from 10-, 21- and 60-day-old rats respectively. Paraffin-embedded testis sections were proce...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2001.0186
更新日期:2001-08-01 00:00:00
abstract::Until primate sperm are exposed to the unique microenvironment of the epididymis, they are not capable of fertilization or vigorous motility. Many of the proteins that contribute to the unique microenvironment of the primate epididymis, and thus to sperm maturation, are dependent on androgens to induce their synthesis...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0164
更新日期:2001-06-01 00:00:00
abstract::Polychlorinated biphenyls (PCBs) are worldwide pollutants and have caused hazardous effects on many animal species including humans. They have been detected in human milk and therefore exposure of newborns to PCBs is unavoidable if they are breast-fed. We present our findings on two experiments performed to test the e...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0168
更新日期:2001-04-01 00:00:00
abstract::Seawater diluted to half (1.750% salinity) is lethal for adult carps after 3 h and 15 min. At lower salinities (0.350%-0.875%), the fish survived for longer periods, but only 0.175% salinity was innocuous. In carps, adapted to 0.175% salinity, the secretory activity of pavement cells was very high and their external r...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0149
更新日期:2001-02-01 00:00:00
abstract:AIM:The mammalian corneal stroma, like some other connective tissues, can absorb fluid, swell and become oedematous. Since studies on the corneal stroma have been carried out with different types of preparations and solutions, inter-study comparisons are very difficult. A study was thus undertaken on a standardised pre...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1016/s0040-8166(00)80004-x
更新日期:2000-12-01 00:00:00
abstract::The periostracum in Unionidae consists of two layers. The outer one is secreted within the periostracal groove, while the inner layer is secreted by the epithelium of the outer mantle fold. The periostracum reaches its maximum thickness at the shell edge, where it reflects onto the shell surface. Biomineralization beg...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0129
更新日期:2000-10-01 00:00:00
abstract::Morphological and functional changes caused by diabetes in the accessory sex organs and especially the prostate have been reported by several investigators. The aim of the present study was to examine the possible deleterious effects of experimentally induced diabetes on the secretory epithelium of the ventral prostat...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0123
更新日期:2000-08-01 00:00:00
abstract::We examined the possibility that chondrocytes in Meckel's cartilage might secrete matrix metalloproteinase-1 (MMP-1) during degradation of the extracellular matrix. Evidence for the secretion of MMP-1 was obtained by immunohistochemical staining and immunoelectron microscopy, in addition to general histochemical stain...
journal_title:Tissue & cell
pub_type: 杂志文章
doi:10.1054/tice.2000.0106
更新日期:2000-06-01 00:00:00